
Nicholas of Cusa (1401-1464). From a painting by Meister des Marienlebens (Master of the Life of the Virgin), located in the hospital at Kues (Germany)
‘The German Idealists showed some interest in Nicholas of Cusa but the real revival of his thought was stimulated by…Ernst Cassirer (1874-1945) who called him “the first modern thinker”…and by…Karl Jaspers.’
Dermot Moran, ‘Nicholas of Cusa and modern philosophy’, The Cambridge Companion in Renaissance Philosophy, Ed., James Hankins, Cambridge University Press, Cambridge, 2007, 173
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‘Who, then, can understand created being by conjoining, in created being, the absolute necessity from which it derives and the contingency without which it does not exist?’
Nicholas of Cusa, De docta ignorantia (‘On Learned Ignorance’, 1440), II, 2, 100
‘since God is Infinite Actuality, He is the cause only of actuality. But the possibility of being exists contingently. Therefore, if the possibility were absolute, on what would it be contingent? Now, the possibility results from the fact that being [which derives] from the First cannot be completely, unqualifiedly, and absolutely actuality. Therefore, the actuality is contracted through the possibility, so that it does not at all exist except in the possibility. And the possibility does not at all exist unless it is contracted through the actuality.’
Ibid.; II, 8, 137
‘since the contraction of possibility is from God and the contraction of actuality is the result of contingency, the world—which, necessarily, is contracted—is contingently finite.’
Ibid.; II, 8, 139
‘without possibility and actuality and the union of the two there is not, and cannot be, anything. For if [anything] lacked any of these, it would not exist. For how would it exist if it were not possible to exist? And how would it exist if it did not actually exist (since existence is actuality)? And if it were possible to exist but it did not exist, in what sense would it exist? (Therefore, it is necessary that there be the union of possibility and actuality.) The possibility-to-exist, actually existing, and the union of the two are not other than one another. Indeed, they are of the same essence, since they constitute only one and the same thing’
Nicholas of Cusa, De possest (‘On Actualised-Possibility’, 1460), 47

G.W.F.Hegel (1770-1831), Anonymous
‘Hegel came forward with the hitherto quite unheard-of propositions that the accidental has a cause because it is accidental, and just as much also has no cause because it is accidental; that the accidental is necessary, that necessity determines itself as chance, and, on the other hand, this chance is rather absolute necessity. (Logik, II, Book III, 2: Reality.) Natural science has simply ignored these propositions as paradoxical trifling, as self-contradictory nonsense, and, as regards theory, has persisted on the one hand in the barrenness of thought of Wolffian metaphysics, according to which a thing is either accidental or necessary, but not both at once; or, on the other hand, in the hardly less thoughtless mechanical determinism which in words denies chance in general only to recognise it in practice in each particular case.
While natural science continued to think in this way, what did it do in the person of Darwin?

Friedrich Engels in 1860
Darwin in his epoch-making work, set out from the widest existing basis of chance. Precisely the infinite, accidental differences between individuals within a single species, differences which become accentuated until they break through the character of the species, and whose immediate causes even can be demonstrated only in extremely few cases, compelled him to question the previous basis of all regularity in biology, viz., the concept of species in its previous metaphysical rigidity and unchangeability. Without the concept of species, however, all science was nothing. All its branches needed the concept of species as basis: human anatomy and comparative anatomy – embryology, zoology, palaeontology, botany, etc., what were they without the concept of species? All their results were not only put in question but directly set aside. Chance overthrows necessity, as conceived hitherto. The previous idea of necessity breaks down. To retain it means dictatorially to impose on nature as a law a human arbitrary determination that is in contradiction to itself and to reality, it means to deny thereby all inner necessity in living nature, it means generally to proclaim the chaotic kingdom of chance to be the sole law of living nature.’
Friedrich Engels, Dialectics of Nature, Progress Publishers, Moscow, 1976, 217-221